Melanoma, also called Malignant Melanoma, is a skin cancer that is serious and aggressive. Other less serious types of skin cancer are more common. The cancer usually occurs on the skin (e.g. where there is a “mole”), but can also occur in the eye (ocular melanoma) or under the ...

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Introduction: Melanoma

Melanoma is the most serious type of skin cancer. Often the first sign of melanoma is a change in the size, shape, color, or feel of a mole. Most melanomas have a black or black-blue area. Melanoma may also ...1

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Symptoms of Melanoma

The ABCDEs of Skin Cancer: Melanoma usually begins as a mole. Twenty years ago, dermatologists noted that the typical warning signs of early melanoma follow an easy-to-remember formula:

  • Asymmetry—the mole is not a circle, but lopsided
  • Borders ...
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Complications of Melanoma

There are three ways that cancer spreads in the body. Cancer can spread through tissue, the lymph system, and the blood:

  • Tissue. The cancer spreads from where it began by growing into nearby areas.
  • Lymph system. The cancer spreads from ...
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Causes of Melanoma

Melanoma is a disease in which malignant (cancer) cells form in melanocytes (cells that color the skin). Melanocytes: Cells that make melanin and are found in the lower part of the epidermis. Melanin is the pigment that gives skin its ...2

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Causes List for Melanoma

Some possible causes of Melanoma or similar disorders may include:3

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Types of Melanoma

When melanoma starts in the skin, it is called cutaneous melanoma. Melanoma may also occur in mucous membranes (thin, moist layers of tissue that cover surfaces such as the lips). When melanoma occurs in the eye, it is called intraocular ...4

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Diagnosis of Melanoma

Tests to diagnose and stage melanoma may include the following:

See the General Information section for a description of these tests and procedures.

Other tests and ...5

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Genetics of Melanoma

Melanoma sometimes runs in families. People who have two or more close relatives (mother, father, sister, brother, or child) with melanoma have an increased chance of melanoma. In rare cases, members of a family will have an inherited disorder, such ...6

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Risk Factors for Melanoma

Your risk for melanoma is higher if members of your family have had skin cancer or if you’ve already had melanoma or other skin cancers. A major risk factor for melanoma is having a large number of moles, or ...7

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Treatments: Melanoma

Pharmacogenomics is also being used for cancer treatment. If testing shows patients with advanced melanoma (skin cancer) have certain variants, 2 new approved drugs can treat them. ...Source: NIH News in Health (NIH)8 ...

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Prevention of Melanoma

Skin Cancer Prevention: Key Points

  • Avoiding risk factors and increasing protective factors may help prevent cancer.
  • Being exposed to ultraviolet radiation is a risk factor for skin cancer.
  • It is not known if the following lower the risk of nonmelanoma skin cancer ...
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Research for Melanoma

Research: What's New Lymphatic mapping and sentinel lymph node biopsy: In 2006, an NCI study showed that a technique called lymphatic mapping and sentinel lymph node biopsy helped some melanoma patients live longer without a recurrence of their disease. The ...9

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Names and Terminology

Synonyms: Malignant melanoma ...Source: GTR (NCBI/NIH)10 ...

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  1. Source: MedLinePlus (NIH): melanoma.html
  2. Source: NCI (NIH): types/ skin/ patient/ melanoma-treatment-pdq
  3. Source: Algorithmically Generated List
  4. Source: NCI (NIH): types/ skin/ patient/ melanoma-treatment-pdq
  5. Source: NCI (NIH): types/ childhood-cancers/ patient/ unusual-cancers-childhood-pdq
  6. Source: NCI (NIH): types/ skin/ moles-fact-sheet
  7. Source: NIH News in Health (NIH): issue/ jul2014/ feature1
  8. Source: NIH News in Health (NIH): issue/ dec2013/ feature1
  9. Source: MedLinePlus Magazine (NIH): magazine/ issues/ spring07/ articles/ spring07pg12.html
  10. Source: GTR (NCBI/NIH): gtr/ conditions/ CN002586/ 

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Note: This site is for informational purposes only and is not medical advice. See your doctor or other qualified medical professional for all your medical needs.